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IRMA™ employs decades of clinical data, cutting-edge machine learning algorithms and the latest breakthroughs in reproductive immunology to identify often-overlooked causes for reproductive failure — and provide expert guidance for personalized follow-up treatment with your own doctor.

Parental Compatibility
(HLA mismatches)

Natural Killer Cell
Cytotoxic Activity

Systemic Inflammation

Thrombophilia

Regulatory T-cell

Autoimmunity

IRMA identifies often-overlooked immunological causes for reproductive failure — and provides expert guidance for individualized treatment with your own doctor.

Sample report How it works

for infertility, miscarriages, complications and IVF failures

of repetitive high-cost low-success fertility treatments

by determining appropriate immunological follow-up care

Pregmune founder Dr. Andrea Vidali explains how IRMA is revolutionizing the treatment of fertility care.

Q1Have you and your partner been trying to conceive for more than 1 year with no success and are seeking answers about the possible causes of your infertility?
Q2Are you seeking answers and treatment for miscarriages or prior failed IVF cycles including with donor egg?
Q3
Do you have a history of any of the following conditions?
- Poor embryo quality
- Recurrent pregnancy loss
- Stillbirth
- Pregnancy complications such as preeclampsia or preterm labor
- Autoimmune diseases
- Endometriosis
- PCOS
- Diminished ovarian reserve

If you answered “yes” to any of these three questions, then IRMA may be a good solution for you.

Speak with a Pregmune fertility services specialist to learn how IRMA can help you on your fertility journey.

Schedule a free call

IRMA is a reproductive immunology assessment that will help identify the potential causes of your infertility, will estimate your chances for successful live birth based on our customized artificial intelligence algorithm, and will provide you with expert guidance for follow-up treatment for improved chance of success.

Patients are responsible for 2 different types of costs:

1) Cost of the IRMA assessment: IRMA costs $1,850 USD (as of 12/01/2023) and must be fully paid by the patient to Pregmune, as out of pocket. It does not include the cost of the blood analysis performed by independent laboratories.

2) Costs of lab work: Lab work will be billed to the patient directly from the laboratory itself. Eligibility and costs of lab work largely depends on the patient’s insurance provider and plan. Please contact Labcorp at +1 (800) 845-6167, ReproSource at +1 (800) 667-8893 and your insurance carrier to ask for support in this regard.

Pregmune providers are out-of-network with all insurance companies. The patient can attempt to submit a claim for reimbursement for the cost of IRMA to their insurance carrier by presenting the statement from Pregmune, which will include all the information and service codes that are required by most insurance carriers in order to evaluate reimbursement eligibility and amount.

Yes. All patients MUST have their own physician (i.e. Primary Care Physician, Reproductive Endocrinologist, OB/GYN) to request a consult to Pregmune by completing and signing the Referral Form. Pregmune will also provide the patient with lab work requisitions listing all tests required to prepare the IRMA report. The patient will need to provide their own physician with the lab work requisitions, so they can process the orders to the labs. Pregmune will automatically receive a copy of lab results from the labs, and then your IRMA report will be prepared. The physician that signs the Referral Form and orders the lab work will receive a copy of the IRMA report and will decide how to implement recommendations in the IRMA report for the patient.

Your IRMA assessment includes a comprehensive report that will assist your physician in diagnosing and treating your reproductive issues. It is advised to consult with your healthcare provider (gynecologist, reproductive endocrinologist or reproductive immunologist) to review the report.